BONE REGENERATION, STRENGTH & INFECTION MITIGATION
STATUS QUO
Most orthopaedic implants, though thought to be favourably inert, are essentially, physiochemically inactive and hence not symbiotic with the biological environment they are placed in. Implant surfaces need to be designed to blend in a more biocompatible manner, mimicing the necessary functional features of the designated physiological location.
QUANTUM PHASE ORTHOPAEDICS
Nanomaterials are proposed for next generation orthopaedic implants, for the creation of surface environments that are more conducive for osteoblast function. Bone substitute nanomaterials whose composition can emulate the hierarchic organization of natural bone, initiate a platform desirable for the formation of an apatite layer. Post-surgical infection rates could be reduced by the use of nano-fibrous membrane wound dressings, functionalized with antibacterial properties provided by biocompatible nanomaterials.
The most notable application of nanotechnology in orthopaedics entails that of drug delivery and nano-therapeutics, to support the treatment of ailments such as bone cancer and arthritis. With evolving research and nanomaterial development methods, nanotechnology is poised to play a useful role, in the orthopaedic domain.
OUR MATERIAL SYSTEMS
NANOARC offers high performance atomically-architectured quantum material powders, for integration within bone and dental implant composite systems. The quantum powders are designed to improve the interaction between implants and bone tissue at atomic scale, while also, supporting the proliferation of osteoblast cells, to aid the bone healing processes.
The quantum powders can either be implemented as composite additives or integral parts of 3D printed orthopaedic implants.
Essentially, high surface area leads to an increase in the overall performance, thus lowering the necessary dose, to deliver the designated functionality.
HOW TO USE ORTHO-Q NANOPOWDERS
I. Mix the nanopowder(s) at the desired dose(s) with your implant composite material and proceed as usual
II. As a coating on the implant surface in the finishing phase to provide antimicrobial protection and to promote bone growth
III. Use as both an integral part of the implant composite in addition to a coating. This approach provides additional protection if the coating on the implant scratches or wears off.
WHAT IS UNIQUE ABOUT ORTHO-Q?
The zone of inhibition (ZOI), is the clear zone surrounding an antimicrobial agent, indicating a complete absence of bacteria on, or within a given perimeter, from an antimicrobial agent. The size of a ZOI depends on the antimicrobial agent composition, particle size and concentration. Quantum materials distinguish themselves from regular materials in terms of their unique and elevated performance, under cirumstances that other materials cannot function in. For example, in antimicrobial settings, quantum materials perform in both illuminated and dark conditions while regular materials often need photo-activation, which is the operation environment of bone/orthopaedic implants
The ZOI with quantum materials, can often double or even quadruple that of regular (nano)materials. With quantum materials, the ZOI can span several centimetres and dental fillings as well as implants can provide antimicrobial protection to prevent infection and minimise the use of antibiotics post implant installation. This advantage, means merely coating an implant or adding ORTHO-Q nanoadditives to an implant composite, they can serve as follows:
active components within the composite of orthopaedic implants for both antimicrobial protection and mechanical strength
active transparent nano-coatings. for antimicrobial protection and better osteoblast adhesion due to the biomimetic nature of the material, in promoting bone growth.
PRODUCTS
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QUARTERLY ( 5 % ) | BI-ANNUALLY ( 10 % ) | ANNUALLY ( 15 % )
ORTHO-Q
NANOARCHITECTURE : ~ 10 nm (0.01 μm) spherical nanoparticles
SURFACE AREA (BET) : 415300 cm²/g
COLOUR : White Nanopowder
DOSAGE IN COMPOSITE : on average 500 – 1000 μg/ml (or 0.5 - 1g per kg of composite mix)
DOSAGE IN COATING : 1000 – 1500 μg/ml
APPLICATIONS : Increase implant compressive strength, anticorrosion, antibacterial protection. Suitable for resin fillings and easy accessibility of ultra-small cracks in bones. Improves mechanical strength of resin fillings and implants
VIEW PRICING
QUANTITY | PRICE
25 grams (0.88 oz.) | $ 3,750
250 grams (8.81 oz.) | $ 36,000
1kg (2.2 lb) | $ 143,000
BULK ORDER RATES : From 1 Tonne | CONTACT trade@nanoarc.org
ORTHO-Q I
NANOARCHITECTURE : Atomically Thin Sheets/Flakes ( < 1 nm Thickness)
SURFACE AREA (BET) : 635200 cm²/g
COLOUR : White Nanopowder
DOSAGE IN COMPOSITE : on average 300 – 700 μg/ml (or 0.3 - 0.7g per kg of composite mix)
DOSAGE IN COATING : 500 – 1000 μg/ml
APPLICATIONS : Increase compressive and tensile strength, anticorrosion, antibacterial and antifungal protection. Suitable for resin fillings and easy accessibility of ultra-small cracks and crevices in bones. Improves mechanical strength of resin fillings and implants
VIEW PRICING
QUANTITY | PRICE
25 grams (0.88 oz.) | $ 4,150
250 grams (8.81 oz.) | $ 40,000
1kg (2.2 lb) | $ 159,000
BULK ORDER RATES : From 1 Tonne | CONTACT trade@nanoarc.org
ORTHO-Q II
NANOARCHITECTURE : Atomically Thin Sheets/Flakes ( < 1 nm Thickness)
SURFACE AREA (BET) : 703000 cm²/g
COLOUR : White Nanopowder
DOSAGE IN COMPOSITE : on average 300 – 700 μg/ml (or 0.3 - 0.7g per kg of composite mix)
DOSAGE IN COATING : 500 – 1000 μg/ml
APPLICATIONS : Drug delivery, osteogenic implant material to promote better adhesion to bone, promote bone growth and repair lesions in bones. Impact-resistant material for composites, grinding media, antimicrobial filter material.
VIEW PRICING
QUANTITY | PRICE
25 grams (0.88 oz.) | $ 4,800
250 grams (8.81 oz.) | $ 47,000
1kg (2.2 lb) | $ 187,000
BULK ORDER RATES : From 1 Tonne | CONTACT trade@nanoarc.org